diff --git a/dev-requirements.txt b/dev-requirements.txt
index 4754221d..1922ad28 100644
--- a/dev-requirements.txt
+++ b/dev-requirements.txt
@@ -19,7 +19,7 @@ cffi==1.7.0
 pycrypto==2.6.1
 pynacl==1.0.1
 cryptography==1.4.0
-securesystemslib==0.10.1
+securesystemslib==0.10.6
 
 # Testing requirements.  The rest of the testing dependencies available in
 # 'tox.ini'
diff --git a/setup.py b/setup.py
index 4a54bad2..6a926834 100755
--- a/setup.py
+++ b/setup.py
@@ -105,7 +105,7 @@
     'Topic :: Security',
     'Topic :: Software Development'
   ],
-   install_requires = ['iso8601', 'six', 'securesystemslib>=0.10.5'],
+   install_requires = ['iso8601', 'six', 'securesystemslib>=0.10.6'],
   packages = find_packages(exclude=['tests']),
   scripts = [
     'tuf/scripts/basic_client.py',