diff --git a/changes/34950-nano-tables-cleanup b/changes/34950-nano-tables-cleanup
new file mode 100644
index 0000000000..313da97dce
--- /dev/null
+++ b/changes/34950-nano-tables-cleanup
@@ -0,0 +1 @@
+* Updated iOS/iPadOS refetch logic to slowly clear out old/stale results
diff --git a/cmd/fleet/cron.go b/cmd/fleet/cron.go
index 006b3b0e52..b0160f433b 100644
--- a/cmd/fleet/cron.go
+++ b/cmd/fleet/cron.go
@@ -1205,6 +1205,9 @@ func newCleanupsAndAggregationSchedule(
 			}
 			return nil
 		}),
+		schedule.WithJob("cleanup_orphaned_nano_refetch_commands", func(ctx context.Context) error {
+			return ds.CleanupOrphanedNanoRefetchCommands(ctx)
+		}),
 	)
 
 	return s, nil
diff --git a/server/datastore/mysql/apple_mdm.go b/server/datastore/mysql/apple_mdm.go
index 16f52edfd6..ca843afdb5 100644
--- a/server/datastore/mysql/apple_mdm.go
+++ b/server/datastore/mysql/apple_mdm.go
@@ -6843,6 +6843,126 @@ WHERE (
 	return nil
 }
 
+func (ds *Datastore) CleanupStaleNanoRefetchCommands(ctx context.Context, enrollmentID string, commandUUIDPrefix string, currentCommandUUID string) error {
+	// Step 1: Get up to 3 old command UUIDs from nano_enrollment_queue for this
+	// enrollment. The PK is (id, command_uuid) so filtering by id first is efficient,
+	// and the LIKE prefix on command_uuid narrows within that enrollment's entries.
+	// 3 may seem like too few but in load testing because of how often this runs it
+	// was found that larger numbers can cause too much contention
+	const selectOldCmds = `
+		SELECT command_uuid FROM nano_enrollment_queue
+		WHERE id = ?
+		  AND command_uuid LIKE ?
+		  AND command_uuid != ?
+		  AND created_at < NOW() - INTERVAL 30 DAY
+		LIMIT 3`
+
+	var oldCmdUUIDs []string
+	if err := sqlx.SelectContext(ctx, ds.reader(ctx), &oldCmdUUIDs, selectOldCmds, enrollmentID, commandUUIDPrefix+"%", currentCommandUUID); err != nil {
+		return ctxerr.Wrap(ctx, err, "select old nano refetch commands")
+	}
+	if len(oldCmdUUIDs) == 0 {
+		return nil
+	}
+
+	// Step 2: From ncr, find which of those command UUIDs have been acknowledged or
+	// errored for this enrollment. The PK (id, command_uuid) makes this efficient
+	// since we provide both id and the command_uuid IN list.
+	selectAckQuery, args, err := sqlx.In(`
+		SELECT command_uuid FROM nano_command_results
+		WHERE id = ? AND command_uuid IN (?) AND status IN ('Acknowledged', 'Error')`,
+		enrollmentID, oldCmdUUIDs)
+	if err != nil {
+		return ctxerr.Wrap(ctx, err, "build IN query for nano command results")
+	}
+
+	var ackCmdUUIDs []string
+	if err := sqlx.SelectContext(ctx, ds.reader(ctx), &ackCmdUUIDs, selectAckQuery, args...); err != nil {
+		return ctxerr.Wrap(ctx, err, "select acknowledged nano command results")
+	}
+	if len(ackCmdUUIDs) == 0 {
+		return nil
+	}
+
+	// Step 3: Delete from neq and ncr in the same transaction, scoped to this enrollment. We may not
+	// need to delete in a transaction here but it's the easiest way to ensure we cleanup ncr and further
+	// we absolutely must ensure we don't delete from ncr before deleting from neq to avoid command resends
+	return ds.withRetryTxx(ctx, func(tx sqlx.ExtContext) error {
+		deleteNEQ, delArgs, err := sqlx.In(
+			`DELETE FROM nano_enrollment_queue WHERE id = ? AND command_uuid IN (?)`,
+			enrollmentID, ackCmdUUIDs)
+		if err != nil {
+			return ctxerr.Wrap(ctx, err, "build delete neq query")
+		}
+		if _, err := tx.ExecContext(ctx, deleteNEQ, delArgs...); err != nil {
+			return ctxerr.Wrap(ctx, err, "delete stale nano enrollment queue entries")
+		}
+
+		deleteNCR, delArgs, err := sqlx.In(
+			`DELETE FROM nano_command_results WHERE id = ? AND command_uuid IN (?)`,
+			enrollmentID, ackCmdUUIDs)
+		if err != nil {
+			return ctxerr.Wrap(ctx, err, "build delete ncr query")
+		}
+		if _, err := tx.ExecContext(ctx, deleteNCR, delArgs...); err != nil {
+			return ctxerr.Wrap(ctx, err, "delete stale nano command results entries")
+		}
+
+		return nil
+	})
+}
+
+func (ds *Datastore) CleanupOrphanedNanoRefetchCommands(ctx context.Context) error {
+	// Find up to 100 old REFETCH- commands. Note I am doing this as two queries since nano_commands
+	// can be large and I want to make sure in the case of a large number of active commands there's
+	// not going to be a full table scan or something happening. This is a best effort deletion so it
+	// is OK if our sample deletes nothing
+	const selectStmt = `
+		SELECT command_uuid FROM nano_commands nc
+		WHERE nc.command_uuid LIKE 'REFETCH-%'
+		  AND nc.created_at < NOW() - INTERVAL 30 DAY
+		LIMIT 100`
+
+	var cmdUUIDs []string
+	if err := sqlx.SelectContext(ctx, ds.reader(ctx), &cmdUUIDs, selectStmt); err != nil {
+		return ctxerr.Wrap(ctx, err, "get mdm apple refetch commands")
+	}
+	if len(cmdUUIDs) == 0 {
+		return nil
+	}
+
+	// Delete those that don't have a corresponding entry in nano_enrollment_queue
+	selectOrphanedCommandsStmt := `
+	SELECT command_uuid FROM nano_commands nc
+	WHERE nc.command_uuid IN (?) AND NOT EXISTS (
+		SELECT 1 FROM nano_enrollment_queue neq
+		WHERE neq.command_uuid = nc.command_uuid AND neq.active = 1
+		LIMIT 1
+	)`
+	selectOrphanedCommandsStmt, args, err := sqlx.In(selectOrphanedCommandsStmt, cmdUUIDs)
+	if err != nil {
+		return ctxerr.Wrap(ctx, err, "build IN query for orphaned refetch commands")
+	}
+	if err := sqlx.SelectContext(ctx, ds.reader(ctx), &cmdUUIDs, selectOrphanedCommandsStmt, args...); err != nil {
+		return ctxerr.Wrap(ctx, err, "get orphaned refetch commands")
+	}
+	if len(cmdUUIDs) == 0 {
+		return nil
+	}
+
+	deleteOrphanedCommandsStmt := `
+	DELETE FROM nano_commands
+	WHERE command_uuid IN (?)`
+	deleteOrphanedCommandsStmt, args, err = sqlx.In(deleteOrphanedCommandsStmt, cmdUUIDs)
+	if err != nil {
+		return ctxerr.Wrap(ctx, err, "build IN query for deleting orphaned refetch commands")
+	}
+	if _, err := ds.writer(ctx).ExecContext(ctx, deleteOrphanedCommandsStmt, args...); err != nil {
+		return ctxerr.Wrap(ctx, err, "delete orphaned refetch commands")
+	}
+	return nil
+}
+
 func (ds *Datastore) GetMDMAppleOSUpdatesSettingsByHostSerial(ctx context.Context, serial string) (string, *fleet.AppleOSUpdateSettings, error) {
 	stmt := `
 SELECT
diff --git a/server/datastore/mysql/apple_mdm_test.go b/server/datastore/mysql/apple_mdm_test.go
index 739fe567a0..c71c731bee 100644
--- a/server/datastore/mysql/apple_mdm_test.go
+++ b/server/datastore/mysql/apple_mdm_test.go
@@ -123,6 +123,8 @@ func TestMDMApple(t *testing.T) {
 		{"GetHostRecoveryLockPasswordStatus", testGetHostRecoveryLockPasswordStatus},
 		{"ClaimHostsForRecoveryLockClear", testClaimHostsForRecoveryLockClear},
 		{"RecoveryLockRotation", testRecoveryLockRotation},
+		{"CleanupStaleNanoRefetchCommands", testCleanupStaleNanoRefetchCommands},
+		{"CleanupOrphanedNanoRefetchCommands", testCleanupOrphanedNanoRefetchCommands},
 		{"RecoveryLockAutoRotation", testRecoveryLockAutoRotation},
 	}
 
@@ -11392,6 +11394,202 @@ func testRecoveryLockRotation(t *testing.T, ds *Datastore) {
 	})
 }
 
+func testCleanupStaleNanoRefetchCommands(t *testing.T, ds *Datastore) {
+	ctx := t.Context()
+
+	// Create a host and enroll it in nano MDM.
+	host, err := ds.NewHost(ctx, &fleet.Host{
+		Hostname:        "test-cleanup-host",
+		OsqueryHostID:   ptr.String("cleanup-osquery-id"),
+		NodeKey:         ptr.String("cleanup-node-key"),
+		UUID:            "cleanup-test-uuid",
+		Platform:        "ios",
+		DetailUpdatedAt: time.Now(),
+		LabelUpdatedAt:  time.Now(),
+		PolicyUpdatedAt: time.Now(),
+		SeenTime:        time.Now(),
+	})
+	require.NoError(t, err)
+	nanoEnroll(t, ds, host, false)
+
+	enrollmentID := host.UUID
+
+	// Helper to insert a nano command with a specific created_at.
+	insertNanoCmd := func(cmdUUID, reqType string, createdAt time.Time) {
+		_, err := ds.writer(ctx).ExecContext(ctx,
+			`INSERT INTO nano_commands (command_uuid, request_type, command, created_at) VALUES (?, ?, '<?xml', ?)`,
+			cmdUUID, reqType, createdAt)
+		require.NoError(t, err)
+	}
+
+	// Helper to insert a nano_enrollment_queue entry.
+	insertNEQ := func(id, cmdUUID string, createdAt time.Time) {
+		_, err := ds.writer(ctx).ExecContext(ctx,
+			`INSERT INTO nano_enrollment_queue (id, command_uuid, active, priority, created_at) VALUES (?, ?, 0, 0, ?)`,
+			id, cmdUUID, createdAt)
+		require.NoError(t, err)
+	}
+
+	// Helper to insert a nano_command_results entry.
+	insertNCR := func(id, cmdUUID, status string) {
+		_, err := ds.writer(ctx).ExecContext(ctx,
+			`INSERT INTO nano_command_results (id, command_uuid, status, result) VALUES (?, ?, ?, '<?xml')`,
+			id, cmdUUID, status)
+		require.NoError(t, err)
+	}
+
+	now := time.Now()
+	oldTime := now.Add(-31 * 24 * time.Hour)   // 31 days ago
+	recentTime := now.Add(-1 * 24 * time.Hour) // 1 day ago
+
+	// Create old REFETCH-APPS- command (should be cleaned up).
+	cmdUUID := "REFETCH-APPS-old-acknowledged"
+	insertNanoCmd(cmdUUID, "InstalledApplicationList", oldTime)
+	insertNEQ(enrollmentID, cmdUUID, oldTime)
+	insertNCR(enrollmentID, cmdUUID, "Acknowledged")
+
+	// Create an old REFETCH-APPS- command that has Error status (should also be cleaned up).
+	insertNanoCmd("REFETCH-APPS-old-error", "InstalledApplicationList", oldTime)
+	insertNEQ(enrollmentID, "REFETCH-APPS-old-error", oldTime)
+	insertNCR(enrollmentID, "REFETCH-APPS-old-error", "Error")
+
+	// Create an old REFETCH-APPS- command with no result (should NOT be cleaned up).
+	insertNanoCmd("REFETCH-APPS-old-noresult", "InstalledApplicationList", oldTime)
+	insertNEQ(enrollmentID, "REFETCH-APPS-old-noresult", oldTime)
+
+	// Create a recent REFETCH-APPS- command (should NOT be cleaned up).
+	insertNanoCmd("REFETCH-APPS-recent", "InstalledApplicationList", recentTime)
+	insertNEQ(enrollmentID, "REFETCH-APPS-recent", recentTime)
+	insertNCR(enrollmentID, "REFETCH-APPS-recent", "Acknowledged")
+
+	// Create old REFETCH-DEVICE- commands (different prefix, should NOT be affected by APPS cleanup).
+	insertNanoCmd("REFETCH-DEVICE-old-0", "DeviceInformation", oldTime)
+	insertNEQ(enrollmentID, "REFETCH-DEVICE-old-0", oldTime)
+	insertNCR(enrollmentID, "REFETCH-DEVICE-old-0", "Acknowledged")
+
+	// The "current" command that triggered the cleanup.
+	currentCmdUUID := "REFETCH-APPS-current"
+	insertNanoCmd(currentCmdUUID, "InstalledApplicationList", now)
+	insertNEQ(enrollmentID, currentCmdUUID, now)
+	insertNCR(enrollmentID, currentCmdUUID, "Acknowledged")
+
+	// Run cleanup for REFETCH-APPS- prefix, scoped to this enrollment.
+	err = ds.CleanupStaleNanoRefetchCommands(ctx, enrollmentID, fleet.RefetchAppsCommandUUIDPrefix, currentCmdUUID)
+	require.NoError(t, err)
+
+	// Verify: old acknowledged/errored REFETCH-APPS- entries should be deleted from neq and ncr.
+	var neqCount int
+	err = sqlx.GetContext(ctx, ds.reader(ctx), &neqCount,
+		`SELECT COUNT(*) FROM nano_enrollment_queue WHERE command_uuid LIKE 'REFETCH-APPS-old-%'`)
+	require.NoError(t, err)
+	// Only the one with no result should remain.
+	assert.Equal(t, 1, neqCount, "only the no-result entry should remain in neq")
+
+	var ncrCount int
+	err = sqlx.GetContext(ctx, ds.reader(ctx), &ncrCount,
+		`SELECT COUNT(*) FROM nano_command_results WHERE command_uuid LIKE 'REFETCH-APPS-old-%'`)
+	require.NoError(t, err)
+	assert.Equal(t, 0, ncrCount, "all old acknowledged/errored ncr entries should be deleted")
+
+	// Verify: recent command should still exist.
+	err = sqlx.GetContext(ctx, ds.reader(ctx), &neqCount,
+		`SELECT COUNT(*) FROM nano_enrollment_queue WHERE command_uuid = 'REFETCH-APPS-recent'`)
+	require.NoError(t, err)
+	assert.Equal(t, 1, neqCount, "recent command should not be deleted")
+
+	// Verify: current command should still exist.
+	err = sqlx.GetContext(ctx, ds.reader(ctx), &neqCount,
+		`SELECT COUNT(*) FROM nano_enrollment_queue WHERE command_uuid = ?`, currentCmdUUID)
+	require.NoError(t, err)
+	assert.Equal(t, 1, neqCount, "current command should not be deleted")
+
+	// Verify: REFETCH-DEVICE- command should not be affected.
+	err = sqlx.GetContext(ctx, ds.reader(ctx), &neqCount,
+		`SELECT COUNT(*) FROM nano_enrollment_queue WHERE command_uuid = 'REFETCH-DEVICE-old-0'`)
+	require.NoError(t, err)
+	assert.Equal(t, 1, neqCount, "different prefix should not be affected")
+}
+
+func testCleanupOrphanedNanoRefetchCommands(t *testing.T, ds *Datastore) {
+	ctx := t.Context()
+
+	// Create a host and enroll it for FK constraints.
+	host, err := ds.NewHost(ctx, &fleet.Host{
+		Hostname:        "test-orphan-host",
+		OsqueryHostID:   ptr.String("orphan-osquery-id"),
+		NodeKey:         ptr.String("orphan-node-key"),
+		UUID:            "orphan-test-uuid",
+		Platform:        "ios",
+		DetailUpdatedAt: time.Now(),
+		LabelUpdatedAt:  time.Now(),
+		PolicyUpdatedAt: time.Now(),
+		SeenTime:        time.Now(),
+	})
+	require.NoError(t, err)
+	nanoEnroll(t, ds, host, false)
+
+	now := time.Now()
+	oldTime := now.Add(-31 * 24 * time.Hour)
+	recentTime := now.Add(-1 * 24 * time.Hour)
+
+	// Insert an old REFETCH command WITH a neq reference (should NOT be deleted).
+	_, err = ds.writer(ctx).ExecContext(ctx,
+		`INSERT INTO nano_commands (command_uuid, request_type, command, created_at) VALUES (?, ?, '<?xml', ?)`,
+		"REFETCH-APPS-with-ref", "InstalledApplicationList", oldTime)
+	require.NoError(t, err)
+	_, err = ds.writer(ctx).ExecContext(ctx,
+		`INSERT INTO nano_enrollment_queue (id, command_uuid, active, priority, created_at) VALUES (?, ?, 1, 0, ?)`,
+		host.UUID, "REFETCH-APPS-with-ref", oldTime)
+	require.NoError(t, err)
+
+	// Insert an old REFETCH command WITHOUT neq reference (should be deleted).
+	_, err = ds.writer(ctx).ExecContext(ctx,
+		`INSERT INTO nano_commands (command_uuid, request_type, command, created_at) VALUES (?, ?, '<?xml', ?)`,
+		"REFETCH-APPS-orphan", "InstalledApplicationList", oldTime)
+	require.NoError(t, err)
+
+	// Insert a recent REFETCH command WITHOUT neq reference (should NOT be deleted - too new).
+	_, err = ds.writer(ctx).ExecContext(ctx,
+		`INSERT INTO nano_commands (command_uuid, request_type, command, created_at) VALUES (?, ?, '<?xml', ?)`,
+		"REFETCH-APPS-recent-orphan", "InstalledApplicationList", recentTime)
+	require.NoError(t, err)
+
+	// Insert an old non-REFETCH command WITHOUT neq reference (should NOT be deleted - wrong prefix).
+	_, err = ds.writer(ctx).ExecContext(ctx,
+		`INSERT INTO nano_commands (command_uuid, request_type, command, created_at) VALUES (?, ?, '<?xml', ?)`,
+		"OTHER-CMD-orphan", "ProfileList", oldTime)
+	require.NoError(t, err)
+
+	// Run cleanup.
+	err = ds.CleanupOrphanedNanoRefetchCommands(ctx)
+	require.NoError(t, err)
+
+	// Verify: old orphaned REFETCH command should be gone.
+	var count int
+	err = sqlx.GetContext(ctx, ds.reader(ctx), &count,
+		`SELECT COUNT(*) FROM nano_commands WHERE command_uuid = 'REFETCH-APPS-orphan'`)
+	require.NoError(t, err)
+	assert.Equal(t, 0, count, "old orphaned REFETCH command should be deleted")
+
+	// Verify: old REFETCH command with reference should still exist.
+	err = sqlx.GetContext(ctx, ds.reader(ctx), &count,
+		`SELECT COUNT(*) FROM nano_commands WHERE command_uuid = 'REFETCH-APPS-with-ref'`)
+	require.NoError(t, err)
+	assert.Equal(t, 1, count, "REFETCH command with neq reference should not be deleted")
+
+	// Verify: recent orphaned REFETCH command should still exist.
+	err = sqlx.GetContext(ctx, ds.reader(ctx), &count,
+		`SELECT COUNT(*) FROM nano_commands WHERE command_uuid = 'REFETCH-APPS-recent-orphan'`)
+	require.NoError(t, err)
+	assert.Equal(t, 1, count, "recent orphaned REFETCH command should not be deleted")
+
+	// Verify: non-REFETCH command should still exist.
+	err = sqlx.GetContext(ctx, ds.reader(ctx), &count,
+		`SELECT COUNT(*) FROM nano_commands WHERE command_uuid = 'OTHER-CMD-orphan'`)
+	require.NoError(t, err)
+	assert.Equal(t, 1, count, "non-REFETCH command should not be deleted")
+}
+
 func testRecoveryLockAutoRotation(t *testing.T, ds *Datastore) {
 	ctx := t.Context()
 
diff --git a/server/fleet/datastore.go b/server/fleet/datastore.go
index 6211adaafd..84e014c966 100644
--- a/server/fleet/datastore.go
+++ b/server/fleet/datastore.go
@@ -421,6 +421,16 @@ type Datastore interface {
 	// CleanupHostMDMAppleProfiles removes abandoned host MDM Apple profiles entries.
 	CleanupHostMDMAppleProfiles(ctx context.Context) error
 
+	// CleanupStaleNanoRefetchCommands deletes up to 3 nano_enrollment_queue and
+	// their corresponding nano_command_results entries for the given enrollment ID
+	// and REFETCH command prefix type that were sent and acknowledged/errored at
+	// least 30 days ago. The current command UUID is excluded from deletion.
+	CleanupStaleNanoRefetchCommands(ctx context.Context, enrollmentID string, commandUUIDPrefix string, currentCommandUUID string) error
+
+	// CleanupOrphanedNanoRefetchCommands deletes up to 100 REFETCH-prefixed nano_commands
+	// older than 30 days that have no remaining references in nano_enrollment_queue.
+	CleanupOrphanedNanoRefetchCommands(ctx context.Context) error
+
 	// IsHostConnectedToFleetMDM verifies if the host has an active Fleet MDM enrollment with this server
 	IsHostConnectedToFleetMDM(ctx context.Context, host *Host) (bool, error)
 
diff --git a/server/mock/datastore_mock.go b/server/mock/datastore_mock.go
index 455057f1ca..770edb2a2c 100644
--- a/server/mock/datastore_mock.go
+++ b/server/mock/datastore_mock.go
@@ -325,6 +325,10 @@ type CleanupHostMDMCommandsFunc func(ctx context.Context) error
 
 type CleanupHostMDMAppleProfilesFunc func(ctx context.Context) error
 
+type CleanupStaleNanoRefetchCommandsFunc func(ctx context.Context, enrollmentID string, commandUUIDPrefix string, currentCommandUUID string) error
+
+type CleanupOrphanedNanoRefetchCommandsFunc func(ctx context.Context) error
+
 type IsHostConnectedToFleetMDMFunc func(ctx context.Context, host *fleet.Host) (bool, error)
 
 type ListHostCertificatesFunc func(ctx context.Context, hostID uint, opts fleet.ListOptions) ([]*fleet.HostCertificateRecord, *fleet.PaginationMetadata, error)
@@ -2301,6 +2305,12 @@ type DataStore struct {
 	CleanupHostMDMAppleProfilesFunc        CleanupHostMDMAppleProfilesFunc
 	CleanupHostMDMAppleProfilesFuncInvoked bool
 
+	CleanupStaleNanoRefetchCommandsFunc        CleanupStaleNanoRefetchCommandsFunc
+	CleanupStaleNanoRefetchCommandsFuncInvoked bool
+
+	CleanupOrphanedNanoRefetchCommandsFunc        CleanupOrphanedNanoRefetchCommandsFunc
+	CleanupOrphanedNanoRefetchCommandsFuncInvoked bool
+
 	IsHostConnectedToFleetMDMFunc        IsHostConnectedToFleetMDMFunc
 	IsHostConnectedToFleetMDMFuncInvoked bool
 
@@ -5644,6 +5654,20 @@ func (s *DataStore) CleanupHostMDMAppleProfiles(ctx context.Context) error {
 	return s.CleanupHostMDMAppleProfilesFunc(ctx)
 }
 
+func (s *DataStore) CleanupStaleNanoRefetchCommands(ctx context.Context, enrollmentID string, commandUUIDPrefix string, currentCommandUUID string) error {
+	s.mu.Lock()
+	s.CleanupStaleNanoRefetchCommandsFuncInvoked = true
+	s.mu.Unlock()
+	return s.CleanupStaleNanoRefetchCommandsFunc(ctx, enrollmentID, commandUUIDPrefix, currentCommandUUID)
+}
+
+func (s *DataStore) CleanupOrphanedNanoRefetchCommands(ctx context.Context) error {
+	s.mu.Lock()
+	s.CleanupOrphanedNanoRefetchCommandsFuncInvoked = true
+	s.mu.Unlock()
+	return s.CleanupOrphanedNanoRefetchCommandsFunc(ctx)
+}
+
 func (s *DataStore) IsHostConnectedToFleetMDM(ctx context.Context, host *fleet.Host) (bool, error) {
 	s.mu.Lock()
 	s.IsHostConnectedToFleetMDMFuncInvoked = true
diff --git a/server/service/apple_mdm.go b/server/service/apple_mdm.go
index d03cd8852a..32ffc211f7 100644
--- a/server/service/apple_mdm.go
+++ b/server/service/apple_mdm.go
@@ -4024,6 +4024,11 @@ func (svc *MDMAppleCheckinAndCommandService) handleRefetchAppsResults(ctx contex
 		}
 	}
 
+	// Best-effort cleanup of stale refetch commands of the same type.
+	if err := svc.ds.CleanupStaleNanoRefetchCommands(ctx, host.UUID, fleet.RefetchAppsCommandUUIDPrefix, cmdResult.CommandUUID); err != nil {
+		svc.logger.ErrorContext(ctx, "cleanup stale nano refetch apps commands", "err", err, "host_uuid", host.UUID, "command_prefix", fleet.RefetchAppsCommandUUIDPrefix)
+	}
+
 	return nil, nil
 }
 
@@ -4552,6 +4557,11 @@ func (svc *MDMAppleCheckinAndCommandService) handleRefetchCertsResults(ctx conte
 		return nil, ctxerr.Wrap(ctx, err, "refetch certs: update host certificates")
 	}
 
+	// Best-effort cleanup of stale refetch commands of the same type.
+	if err := svc.ds.CleanupStaleNanoRefetchCommands(ctx, host.UUID, fleet.RefetchCertsCommandUUIDPrefix, cmdResult.CommandUUID); err != nil {
+		svc.logger.ErrorContext(ctx, "cleanup stale nano refetch certs commands", "err", err, "host_uuid", host.UUID, "command_prefix", fleet.RefetchCertsCommandUUIDPrefix)
+	}
+
 	return nil, nil
 }
 
@@ -4660,6 +4670,11 @@ func (svc *MDMAppleCheckinAndCommandService) handleRefetchDeviceResults(ctx cont
 		}
 	}
 
+	// Best-effort cleanup of stale refetch commands of the same type.
+	if err := svc.ds.CleanupStaleNanoRefetchCommands(ctx, host.UUID, fleet.RefetchDeviceCommandUUIDPrefix, cmdResult.CommandUUID); err != nil {
+		svc.logger.ErrorContext(ctx, "cleanup stale nano refetch device commands", "err", err, "host_uuid", host.UUID, "command_prefix", fleet.RefetchDeviceCommandUUIDPrefix)
+	}
+
 	return nil, nil
 }
 
diff --git a/server/service/apple_mdm_test.go b/server/service/apple_mdm_test.go
index addbdcb147..3b5113d72a 100644
--- a/server/service/apple_mdm_test.go
+++ b/server/service/apple_mdm_test.go
@@ -4924,6 +4924,12 @@ func TestMDMCommandAndReportResultsIOSIPadOSRefetch(t *testing.T) {
 		require.Equal(t, lostModeCommandUUID, commandUUID)
 		return nil
 	}
+	ds.CleanupStaleNanoRefetchCommandsFunc = func(ctx context.Context, enrollmentID string, commandUUIDPrefix string, currentCommandUUID string) error {
+		require.Equal(t, hostUUID, enrollmentID)
+		require.Equal(t, fleet.RefetchDeviceCommandUUIDPrefix, commandUUIDPrefix)
+		require.Equal(t, commandUUID, currentCommandUUID)
+		return nil
+	}
 
 	_, err := svc.CommandAndReportResults(
 		&mdm.Request{Context: ctx},