diff --git a/changes/15253-sort-results-case-insensitively b/changes/15253-sort-results-case-insensitively
new file mode 100644
index 0000000000..3862ebbbf0
--- /dev/null
+++ b/changes/15253-sort-results-case-insensitively
@@ -0,0 +1,2 @@
+* Sort query results and reports case insensitively, and default to sorting by the host display name
+column
diff --git a/frontend/pages/hosts/details/HostQueryReport/HQRTable/HQRTableConfig.tsx b/frontend/pages/hosts/details/HostQueryReport/HQRTable/HQRTableConfig.tsx
index 1245f15ba1..78e65e38bf 100644
--- a/frontend/pages/hosts/details/HostQueryReport/HQRTable/HQRTableConfig.tsx
+++ b/frontend/pages/hosts/details/HostQueryReport/HQRTable/HQRTableConfig.tsx
@@ -59,6 +59,7 @@ const generateColumnConfigs = (rows: Record<string, string>[]) =>
       Filter: DefaultColumnFilter, // Component hides filter for last_fetched
       filterType: "text",
       disableSortBy: false,
+      sortType: "caseInsensitive",
     };
   });
 
diff --git a/frontend/pages/queries/details/components/QueryReport/QueryReport.tsx b/frontend/pages/queries/details/components/QueryReport/QueryReport.tsx
index a1fb6dd63d..e7e7c1807e 100644
--- a/frontend/pages/queries/details/components/QueryReport/QueryReport.tsx
+++ b/frontend/pages/queries/details/components/QueryReport/QueryReport.tsx
@@ -154,6 +154,7 @@ const QueryReport = ({
               />
             );
           }}
+          defaultSortHeader="last_fetched"
           isLoading={false}
           isClientSidePagination
           isClientSideFilter
diff --git a/frontend/pages/queries/details/components/QueryReport/QueryReportTableConfig.tsx b/frontend/pages/queries/details/components/QueryReport/QueryReportTableConfig.tsx
index 4c9af9723b..ed526a261a 100644
--- a/frontend/pages/queries/details/components/QueryReport/QueryReportTableConfig.tsx
+++ b/frontend/pages/queries/details/components/QueryReport/QueryReportTableConfig.tsx
@@ -88,6 +88,7 @@ const generateReportColumnConfigsFromResults = (results: any[]): Column[] => {
       Filter: DefaultColumnFilter, // Component hides filter for last_fetched
       filterType: "text",
       disableSortBy: false,
+      sortType: "caseInsensitive",
     };
   });
   return _unshiftHostname(columnConfigs);
diff --git a/frontend/pages/queries/edit/components/QueryResults/QueryResults.tsx b/frontend/pages/queries/edit/components/QueryResults/QueryResults.tsx
index d871253183..3056c3200f 100644
--- a/frontend/pages/queries/edit/components/QueryResults/QueryResults.tsx
+++ b/frontend/pages/queries/edit/components/QueryResults/QueryResults.tsx
@@ -198,6 +198,7 @@ const QueryResults = ({
     return (
       <div className={`${baseClass}__results-table-container`}>
         <TableContainer
+          defaultSortHeader="host_display_name"
           columnConfigs={
             tableType === "results" ? resultsColumnConfigs : errorColumnConfigs
           }
diff --git a/frontend/pages/queries/edit/components/QueryResults/QueryResultsTableConfig.tsx b/frontend/pages/queries/edit/components/QueryResults/QueryResultsTableConfig.tsx
index 05ea17d2db..3597a7ff97 100644
--- a/frontend/pages/queries/edit/components/QueryResults/QueryResultsTableConfig.tsx
+++ b/frontend/pages/queries/edit/components/QueryResults/QueryResultsTableConfig.tsx
@@ -75,6 +75,7 @@ const generateColumnConfigsFromRows = (
       },
       Filter: DefaultColumnFilter,
       disableSortBy: false,
+      sortType: "caseInsensitive",
     };
   });
   return _unshiftHostname(columnsConfigs);