diff --git a/integration/animations/e2e/src/animations.e2e-spec.ts b/integration/animations/e2e/src/animations.e2e-spec.ts
index 5e5c3bc5e87..a20e046651a 100644
--- a/integration/animations/e2e/src/animations.e2e-spec.ts
+++ b/integration/animations/e2e/src/animations.e2e-spec.ts
@@ -114,4 +114,23 @@ describe('Animations Integration', () => {
       'Nested child component should have been removed immediately during routing',
     );
   });
+
+  it('should remove elements from DOM after reordering and removal with (animate.leave)', async () => {
+    // Wait for the test elements to be rendered
+    await page.waitForSelector('.test-item');
+
+    let items = await page.$$('.test-item');
+    expect(items.length).toBe(2);
+
+    // Shuffle
+    await page.click('#shuffle-test');
+    await new Promise((res) => setTimeout(res, 500));
+
+    // Remove
+    await page.click('#remove-test');
+    await new Promise((res) => setTimeout(res, 500));
+
+    items = await page.$$('.test-item');
+    expect(items.length).toBe(1);
+  });
 });
diff --git a/integration/animations/src/app/app.component.html b/integration/animations/src/app/app.component.html
index 11b1f49aa91..ec2966b9854 100644
--- a/integration/animations/src/app/app.component.html
+++ b/integration/animations/src/app/app.component.html
@@ -17,3 +17,11 @@
 }
 
 <button id="hide-and-intercept" (click)="hideAndIntercept()">Hide and Intercept</button>
+
+<div class="test-reorder-container">
+  @for (item of testItems; track item) {
+    <div class="test-item" (animate.leave)="onTestLeave($event)">Item {{ item }}</div>
+  }
+</div>
+<button id="shuffle-test" (click)="shuffleTest()">Shuffle Test</button>
+<button id="remove-test" (click)="removeTest()">Remove Test</button>
diff --git a/integration/animations/src/app/home.component.ts b/integration/animations/src/app/home.component.ts
index 7a3deeba284..add64699498 100644
--- a/integration/animations/src/app/home.component.ts
+++ b/integration/animations/src/app/home.component.ts
@@ -1,4 +1,4 @@
-import {Component} from '@angular/core';
+import {Component, AnimationCallbackEvent} from '@angular/core';
 import {
   CdkDragDrop,
   CdkDropList,
@@ -20,6 +20,8 @@ export class HomeComponent {
     'Episode III - Revenge of the Sith',
   ];
 
+  testItems = ['A', 'B'];
+
   showFallback = true;
 
   drop(event: CdkDragDrop<string[]>) {
@@ -39,4 +41,16 @@ export class HomeComponent {
     }
     this.showFallback = false;
   }
+
+  shuffleTest() {
+    this.testItems = ['B', 'A'];
+  }
+
+  removeTest() {
+    this.testItems = ['A'];
+  }
+
+  onTestLeave(event: AnimationCallbackEvent) {
+    event.animationComplete();
+  }
 }
diff --git a/packages/core/src/render3/node_manipulation.ts b/packages/core/src/render3/node_manipulation.ts
index a6f16aeebfe..ea147f04bf7 100644
--- a/packages/core/src/render3/node_manipulation.ts
+++ b/packages/core/src/render3/node_manipulation.ts
@@ -150,6 +150,7 @@ function applyToElementOrContainer(
       if (parentLView?.[ANIMATIONS]?.leave?.has(tNode.index)) {
         trackLeavingNodes(tNode, rNode as HTMLElement);
       }
+      reusedNodes.delete(rNode as HTMLElement);
       runLeaveAnimationsWithCallback(
         parentLView,
         tNode,
@@ -166,6 +167,7 @@ function applyToElementOrContainer(
         },
       );
     } else if (action === WalkTNodeTreeAction.Destroy) {
+      reusedNodes.delete(rNode as HTMLElement);
       runLeaveAnimationsWithCallback(parentLView, tNode, injector, () => {
         renderer.destroyNode!(rNode);
       });
diff --git a/packages/core/test/acceptance/animation_spec.ts b/packages/core/test/acceptance/animation_spec.ts
index 7279a98ab80..f122a557afa 100644
--- a/packages/core/test/acceptance/animation_spec.ts
+++ b/packages/core/test/acceptance/animation_spec.ts
@@ -38,6 +38,7 @@ import {tickAnimationFrames} from '../animation_utils/tick_animation_frames';
 import {BrowserTestingModule, platformBrowserTesting} from '@angular/platform-browser/testing';
 import {NoopAnimationsModule} from '@angular/platform-browser/animations';
 import {ComponentRef} from '@angular/core/src/render3';
+import {reusedNodes} from '../../src/animation/utils';
 
 @NgModule({
   providers: [provideZonelessChangeDetection()],
@@ -511,6 +512,60 @@ describe('Animation', () => {
       expect(fadeCalled).toHaveBeenCalled();
     }));
 
+    it('should remove element from DOM with (animate.leave) after list reordering', async () => {
+      @Component({
+        selector: 'leak-cmp',
+        template: 'item',
+      })
+      class LeakComponent {}
+
+      @Component({
+        selector: 'test-cmp',
+        imports: [LeakComponent],
+        template: `
+          @for (item of items(); track item.id) {
+            <leak-cmp (animate.leave)="onLeave($event)" />
+          }
+        `,
+      })
+      class TestComponent {
+        items = signal([{id: '1'}, {id: '2'}]);
+
+        onLeave(event: AnimationCallbackEvent) {
+          event.animationComplete();
+        }
+
+        shuffle() {
+          const arr = this.items();
+          this.items.set([arr[1], arr[0]]);
+        }
+
+        remove() {
+          const arr = this.items();
+          this.items.set([arr[1]]);
+        }
+      }
+
+      TestBed.configureTestingModule({animationsEnabled: true});
+      const fixture = TestBed.createComponent(TestComponent);
+      await fixture.whenStable();
+
+      expect(fixture.nativeElement.textContent).toContain('item');
+
+      fixture.componentInstance.shuffle();
+      await fixture.whenStable();
+
+      const elementsBeforeRemove = fixture.debugElement.queryAll(By.css('leak-cmp'));
+      // Element is in reused nodes before remove
+      expect(reusedNodes.has(elementsBeforeRemove[0].nativeElement)).toBe(true);
+
+      fixture.componentInstance.remove();
+      await fixture.whenStable();
+
+      const elements = fixture.nativeElement.querySelectorAll('leak-cmp');
+      expect(elements.length).toBe(1);
+    });
+
     it('should compose class list when host binding and regular binding', fakeAsync(() => {
       const multiple = `
         .slide-out {