diff --git a/goldens/public-api/common/common.md b/goldens/public-api/common/common.md
index 3b7c57a281e..19d4c52758c 100644
--- a/goldens/public-api/common/common.md
+++ b/goldens/public-api/common/common.md
@@ -308,7 +308,7 @@ export class KeyValuePipe implements PipeTransform {
 }
 
 // @public
-class Location_2 {
+class Location_2 implements OnDestroy {
     constructor(platformStrategy: LocationStrategy, platformLocation: PlatformLocation);
     back(): void;
     forward(): void;
@@ -317,9 +317,11 @@ class Location_2 {
     historyGo(relativePosition?: number): void;
     isCurrentPathEqualTo(path: string, query?: string): boolean;
     static joinWithSlash: (start: string, end: string) => string;
+    // (undocumented)
+    ngOnDestroy(): void;
     normalize(url: string): string;
     static normalizeQueryParams: (params: string) => string;
-    onUrlChange(fn: (url: string, state: unknown) => void): void;
+    onUrlChange(fn: (url: string, state: unknown) => void): VoidFunction;
     path(includeHash?: boolean): string;
     prepareExternalUrl(url: string): string;
     replaceState(path: string, query?: string, state?: any): void;
diff --git a/goldens/public-api/common/testing/testing.md b/goldens/public-api/common/testing/testing.md
index b98a5e1701c..d28b832f9b0 100644
--- a/goldens/public-api/common/testing/testing.md
+++ b/goldens/public-api/common/testing/testing.md
@@ -120,9 +120,11 @@ export class SpyLocation implements Location_2 {
     // (undocumented)
     isCurrentPathEqualTo(path: string, query?: string): boolean;
     // (undocumented)
+    ngOnDestroy(): void;
+    // (undocumented)
     normalize(url: string): string;
     // (undocumented)
-    onUrlChange(fn: (url: string, state: unknown) => void): void;
+    onUrlChange(fn: (url: string, state: unknown) => void): VoidFunction;
     // (undocumented)
     path(): string;
     // (undocumented)
diff --git a/packages/common/src/location/location.ts b/packages/common/src/location/location.ts
index 4df0e7f420e..1c765627314 100644
--- a/packages/common/src/location/location.ts
+++ b/packages/common/src/location/location.ts
@@ -6,8 +6,9 @@
  * found in the LICENSE file at https://angular.io/license
  */
 
-import {EventEmitter, Injectable, ɵɵinject} from '@angular/core';
+import {EventEmitter, Injectable, OnDestroy, ɵɵinject} from '@angular/core';
 import {SubscriptionLike} from 'rxjs';
+
 import {LocationStrategy} from './location_strategy';
 import {PlatformLocation} from './platform_location';
 import {joinWithSlash, normalizeQueryParams, stripTrailingSlash} from './util';
@@ -53,7 +54,7 @@ export interface PopStateEvent {
   // See #23917
   useFactory: createLocation,
 })
-export class Location {
+export class Location implements OnDestroy {
   /** @internal */
   _subject: EventEmitter<any> = new EventEmitter();
   /** @internal */
@@ -65,7 +66,7 @@ export class Location {
   /** @internal */
   _urlChangeListeners: ((url: string, state: unknown) => void)[] = [];
   /** @internal */
-  _urlChangeSubscription?: SubscriptionLike;
+  _urlChangeSubscription: SubscriptionLike|null = null;
 
   constructor(platformStrategy: LocationStrategy, platformLocation: PlatformLocation) {
     this._platformStrategy = platformStrategy;
@@ -82,6 +83,12 @@ export class Location {
     });
   }
 
+  /** @nodoc */
+  ngOnDestroy(): void {
+    this._urlChangeSubscription?.unsubscribe();
+    this._urlChangeListeners = [];
+  }
+
   /**
    * Normalizes the URL path for this location.
    *
@@ -209,8 +216,9 @@ export class Location {
    * framework that are not detectible through "popstate" or "hashchange" events.
    *
    * @param fn The change handler function, which take a URL and a location history state.
+   * @returns A function that, when executed, unregisters a URL change listener.
    */
-  onUrlChange(fn: (url: string, state: unknown) => void) {
+  onUrlChange(fn: (url: string, state: unknown) => void): VoidFunction {
     this._urlChangeListeners.push(fn);
 
     if (!this._urlChangeSubscription) {
@@ -218,6 +226,16 @@ export class Location {
         this._notifyUrlChangeListeners(v.url, v.state);
       });
     }
+
+    return () => {
+      const fnIndex = this._urlChangeListeners.indexOf(fn);
+      this._urlChangeListeners.splice(fnIndex, 1);
+
+      if (this._urlChangeListeners.length === 0) {
+        this._urlChangeSubscription?.unsubscribe();
+        this._urlChangeSubscription = null;
+      }
+    };
   }
 
   /** @internal */
diff --git a/packages/common/testing/src/location_mock.ts b/packages/common/testing/src/location_mock.ts
index 0c6a8e6f8f8..e53025b9a54 100644
--- a/packages/common/testing/src/location_mock.ts
+++ b/packages/common/testing/src/location_mock.ts
@@ -33,7 +33,12 @@ export class SpyLocation implements Location {
   /** @internal */
   _urlChangeListeners: ((url: string, state: unknown) => void)[] = [];
   /** @internal */
-  _urlChangeSubscription?: SubscriptionLike;
+  _urlChangeSubscription: SubscriptionLike|null = null;
+
+  ngOnDestroy(): void {
+    this._urlChangeSubscription?.unsubscribe();
+    this._urlChangeListeners = [];
+  }
 
   setInitialPath(url: string) {
     this._history[this._historyIndex].path = url;
@@ -138,7 +143,7 @@ export class SpyLocation implements Location {
     }
   }
 
-  onUrlChange(fn: (url: string, state: unknown) => void) {
+  onUrlChange(fn: (url: string, state: unknown) => void): VoidFunction {
     this._urlChangeListeners.push(fn);
 
     if (!this._urlChangeSubscription) {
@@ -146,6 +151,16 @@ export class SpyLocation implements Location {
         this._notifyUrlChangeListeners(v.url, v.state);
       });
     }
+
+    return () => {
+      const fnIndex = this._urlChangeListeners.indexOf(fn);
+      this._urlChangeListeners.splice(fnIndex, 1);
+
+      if (this._urlChangeListeners.length === 0) {
+        this._urlChangeSubscription?.unsubscribe();
+        this._urlChangeSubscription = null;
+      }
+    };
   }
 
   /** @internal */
diff --git a/packages/router/test/bootstrap.spec.ts b/packages/router/test/bootstrap.spec.ts
index ff425ca1410..f9699a5c02e 100644
--- a/packages/router/test/bootstrap.spec.ts
+++ b/packages/router/test/bootstrap.spec.ts
@@ -6,7 +6,7 @@
  * found in the LICENSE file at https://angular.io/license
  */
 
-import {APP_BASE_HREF, DOCUMENT, ɵgetDOM as getDOM} from '@angular/common';
+import {APP_BASE_HREF, DOCUMENT, Location, ɵgetDOM as getDOM} from '@angular/common';
 import {ApplicationRef, Component, CUSTOM_ELEMENTS_SCHEMA, destroyPlatform, NgModule} from '@angular/core';
 import {inject} from '@angular/core/testing';
 import {BrowserModule} from '@angular/platform-browser';
@@ -407,6 +407,51 @@ describe('bootstrap', () => {
     expect(window.removeEventListener).toHaveBeenCalledWith('hashchange', jasmine.any(Function));
   });
 
+  it('should unregister a URL change listener and unsubscribe from URL changes when the root view is removed',
+     async () => {
+       const changeListener = jasmine.createSpy('changeListener');
+
+       @Component({template: 'second simple'})
+       class SecondSimpleCmp {
+       }
+
+       @NgModule({
+         imports: [
+           BrowserModule,
+           RouterModule.forRoot(
+               [{path: 'a', component: SimpleCmp}, {path: 'b', component: SecondSimpleCmp}],
+               {initialNavigation: 'enabled'})
+         ],
+         declarations: [RootCmp, SimpleCmp, SecondSimpleCmp],
+         bootstrap: [RootCmp],
+         providers: testProviders
+       })
+       class TestModule {
+       }
+
+       const ngModuleRef = await platformBrowserDynamic().bootstrapModule(TestModule);
+       const router = ngModuleRef.injector.get(Router);
+       const location = ngModuleRef.injector.get(Location);
+
+       const removeUrlChangeFn = location.onUrlChange(changeListener);
+
+       await router.navigateByUrl('/a');
+       expect(changeListener).toHaveBeenCalledTimes(1);
+
+       removeUrlChangeFn();
+       await router.navigateByUrl('/b');
+       expect(changeListener).toHaveBeenCalledTimes(1);
+
+       location.onUrlChange((url: string, state: unknown) => {});
+
+       ngModuleRef.destroy();
+
+       // Let's ensure that URL change listeners are unregistered when the root view is removed,
+       // tho the last returned `onUrlChange` function hasn't been invoked.
+       expect((location as any)._urlChangeListeners.length).toEqual(0);
+       expect((location as any)._urlChangeSubscription.closed).toEqual(true);
+     });
+
   it('can schedule a navigation from the NavigationEnd event #37460', async (done) => {
     @NgModule({
       imports: [