diff --git a/goldens/public-api/core/errors.md b/goldens/public-api/core/errors.md
index c433d0ea21e..3838e00d62b 100644
--- a/goldens/public-api/core/errors.md
+++ b/goldens/public-api/core/errors.md
@@ -75,6 +75,8 @@ export const enum RuntimeErrorCode {
     // (undocumented)
     RECURSIVE_APPLICATION_REF_TICK = 101,
     // (undocumented)
+    RENDERER_NOT_FOUND = 407,
+    // (undocumented)
     TEMPLATE_STRUCTURE_ERROR = 305,
     // (undocumented)
     TYPE_IS_NOT_STANDALONE = 907,
diff --git a/packages/core/src/errors.ts b/packages/core/src/errors.ts
index 89fd475d8ff..003f795e977 100644
--- a/packages/core/src/errors.ts
+++ b/packages/core/src/errors.ts
@@ -50,6 +50,7 @@ export const enum RuntimeErrorCode {
   PLATFORM_ALREADY_DESTROYED = 404,
   ASYNC_INITIALIZERS_STILL_RUNNING = 405,
   APPLICATION_REF_ALREADY_DESTROYED = 406,
+  RENDERER_NOT_FOUND = 407,
 
   // Styling Errors
 
diff --git a/packages/core/src/render3/component_ref.ts b/packages/core/src/render3/component_ref.ts
index 1c37c463791..4ac1ba80d4b 100644
--- a/packages/core/src/render3/component_ref.ts
+++ b/packages/core/src/render3/component_ref.ts
@@ -11,6 +11,7 @@ import {Injector} from '../di/injector';
 import {InjectFlags} from '../di/interface/injector';
 import {ProviderToken} from '../di/provider_token';
 import {EnvironmentInjector} from '../di/r3_injector';
+import {RuntimeError, RuntimeErrorCode} from '../errors';
 import {Type} from '../interface/type';
 import {ComponentFactory as viewEngine_ComponentFactory, ComponentRef as viewEngine_ComponentRef} from '../linker/component_factory';
 import {ComponentFactoryResolver as viewEngine_ComponentFactoryResolver} from '../linker/component_factory_resolver';
@@ -28,7 +29,6 @@ import {NodeInjector} from './di';
 import {createLView, createTView, locateHostElement, renderView} from './instructions/shared';
 import {ComponentDef} from './interfaces/definition';
 import {TContainerNode, TElementContainerNode, TElementNode, TNode} from './interfaces/node';
-import {domRendererFactory3, RendererFactory} from './interfaces/renderer';
 import {RNode} from './interfaces/renderer_dom';
 import {HEADER_OFFSET, LView, LViewFlags, TViewType} from './interfaces/view';
 import {MATH_ML_NAMESPACE, SVG_NAMESPACE} from './namespaces';
@@ -144,9 +144,15 @@ export class ComponentFactory<T> extends viewEngine_ComponentFactory<T> {
     const rootViewInjector =
         realEnvironmentInjector ? new ChainedInjector(injector, realEnvironmentInjector) : injector;
 
-    const rendererFactory =
-        rootViewInjector.get(RendererFactory2, domRendererFactory3 as RendererFactory2) as
-        RendererFactory;
+    const rendererFactory = rootViewInjector.get(RendererFactory2, null);
+    if (rendererFactory === null) {
+      throw new RuntimeError(
+          RuntimeErrorCode.RENDERER_NOT_FOUND,
+          ngDevMode &&
+              'Angular was not able to inject a renderer (RendererFactory2). ' +
+                  'Likely this is due to a broken DI hierarchy. ' +
+                  'Make sure that any injector used to create this component has a correct parent.');
+    }
     const sanitizer = rootViewInjector.get(Sanitizer, null);
 
     const hostRenderer = rendererFactory.createRenderer(null, this.componentDef);
diff --git a/packages/core/test/bundling/animations/bundle.golden_symbols.json b/packages/core/test/bundling/animations/bundle.golden_symbols.json
index cb6807bd6b7..a95927a3124 100644
--- a/packages/core/test/bundling/animations/bundle.golden_symbols.json
+++ b/packages/core/test/bundling/animations/bundle.golden_symbols.json
@@ -722,9 +722,6 @@
   {
     "name": "diPublicInInjector"
   },
-  {
-    "name": "domRendererFactory3"
-  },
   {
     "name": "empty"
   },
diff --git a/packages/core/test/bundling/cyclic_import/bundle.golden_symbols.json b/packages/core/test/bundling/cyclic_import/bundle.golden_symbols.json
index dc04f5c827b..61284fe6c14 100644
--- a/packages/core/test/bundling/cyclic_import/bundle.golden_symbols.json
+++ b/packages/core/test/bundling/cyclic_import/bundle.golden_symbols.json
@@ -509,9 +509,6 @@
   {
     "name": "diPublicInInjector"
   },
-  {
-    "name": "domRendererFactory3"
-  },
   {
     "name": "empty"
   },
diff --git a/packages/core/test/bundling/forms_reactive/bundle.golden_symbols.json b/packages/core/test/bundling/forms_reactive/bundle.golden_symbols.json
index 15c9a3ad004..c381a42d5d3 100644
--- a/packages/core/test/bundling/forms_reactive/bundle.golden_symbols.json
+++ b/packages/core/test/bundling/forms_reactive/bundle.golden_symbols.json
@@ -743,9 +743,6 @@
   {
     "name": "diPublicInInjector"
   },
-  {
-    "name": "domRendererFactory3"
-  },
   {
     "name": "empty"
   },
diff --git a/packages/core/test/bundling/forms_template_driven/bundle.golden_symbols.json b/packages/core/test/bundling/forms_template_driven/bundle.golden_symbols.json
index be3689fb492..67d1ab37a46 100644
--- a/packages/core/test/bundling/forms_template_driven/bundle.golden_symbols.json
+++ b/packages/core/test/bundling/forms_template_driven/bundle.golden_symbols.json
@@ -716,9 +716,6 @@
   {
     "name": "diPublicInInjector"
   },
-  {
-    "name": "domRendererFactory3"
-  },
   {
     "name": "empty"
   },
diff --git a/packages/core/test/bundling/hello_world/bundle.golden_symbols.json b/packages/core/test/bundling/hello_world/bundle.golden_symbols.json
index 0e2dc92658d..887a506d4b3 100644
--- a/packages/core/test/bundling/hello_world/bundle.golden_symbols.json
+++ b/packages/core/test/bundling/hello_world/bundle.golden_symbols.json
@@ -365,9 +365,6 @@
   {
     "name": "detachMovedView"
   },
-  {
-    "name": "domRendererFactory3"
-  },
   {
     "name": "empty"
   },
diff --git a/packages/core/test/bundling/router/bundle.golden_symbols.json b/packages/core/test/bundling/router/bundle.golden_symbols.json
index 9fba68e4330..011e910f53e 100644
--- a/packages/core/test/bundling/router/bundle.golden_symbols.json
+++ b/packages/core/test/bundling/router/bundle.golden_symbols.json
@@ -1028,9 +1028,6 @@
   {
     "name": "dispatch"
   },
-  {
-    "name": "domRendererFactory3"
-  },
   {
     "name": "empty"
   },
diff --git a/packages/core/test/bundling/standalone_bootstrap/bundle.golden_symbols.json b/packages/core/test/bundling/standalone_bootstrap/bundle.golden_symbols.json
index 422e106b453..2f807cf07c8 100644
--- a/packages/core/test/bundling/standalone_bootstrap/bundle.golden_symbols.json
+++ b/packages/core/test/bundling/standalone_bootstrap/bundle.golden_symbols.json
@@ -434,9 +434,6 @@
   {
     "name": "detachMovedView"
   },
-  {
-    "name": "domRendererFactory3"
-  },
   {
     "name": "empty"
   },
diff --git a/packages/core/test/bundling/todo/bundle.golden_symbols.json b/packages/core/test/bundling/todo/bundle.golden_symbols.json
index b6a26af5535..d95b7b1bea0 100644
--- a/packages/core/test/bundling/todo/bundle.golden_symbols.json
+++ b/packages/core/test/bundling/todo/bundle.golden_symbols.json
@@ -626,9 +626,6 @@
   {
     "name": "diPublicInInjector"
   },
-  {
-    "name": "domRendererFactory3"
-  },
   {
     "name": "empty"
   },